Cannabis-based therapies With Dr. Stephanie McGrath
Cannabis-based therapies With Dr. Stephanie McGrath, Associate Professor, Neurology at Veterinary Teaching Hospital at Colorado State University today on It’s A Dog’s life with Angela Ardolino. Dr. McGrath is an absolute rising star in the field of veterinary CBD research and she’s leading the pack with cutting-edge clinical trials and groundbreaking discoveries about dogs with epilepsy and other neurological diseases. We’re biased because we’ve had the pleasure of working with Dr. McGrath, but we think no matter who you are, you’re bound to be blown away by this veterinary superstar. Cannabis-based therapies have been used for centuries for various medicinal purposes. They have recently gained publicity as an effective medication for use in human medicine and, as such, awareness is increasing among veterinarians and pet owners. However, side effects, pharmacokinetics, and efficacy in dogs are not known.
At Colorado State University, they have successfully performed safety and pharmacokinetic study to assess the measurability and tolerability of cannabidiol (CBD) in healthy dogs. The results of this study showed that cannabidiol seemed to be well tolerated in dogs and exposure was dose-proportional. These results provided a framework for our clinical trials in both canine osteoarthritis and canine epilepsy. The objective of our clinical trials was to compare cannabidiol with a placebo for the treatment of naturally occurring canine osteoarthritis and epilepsy. Both studies were double-blinded, placebo-controlled, randomized clinical trials using client-owned dogs with naturally occurring diseases. Osteoarthritis and epilepsy are devastating to our veterinary patients and neither has an ideal treatment to date. If these current and future studies can demonstrate that dogs attain sufficient blood exposure with oral dosing and that CBD is an efficacious drug, it has the potential to improve the quality of life of this population of dogs, as well as decrease the rate of euthanasia. Today’s show will address past studies in veterinary medicine, ongoing studies, future directives, and practical tips for veterinarians, and much more.