SSRI’s, Antidepressants, and Psilocybin


SSRI’s, antidepressants, and psilocybin–can you combine them? Many people are seeking an intentional psilocybin experience in order to combat depression, but very few know whether they can stay on their pharmaceutical medication or not. Some of these medications are medically contraindicated and some are not. 


Hosts Nicholas Levich and Jimmy Nguyen address the various types of medications (not just antidepressants) and how they can impact the psychedelic experience. They provide some general guidelines as well as actionable advice for anyone who is currently taking prescription medication and considering a psychedelic journey. 


On this episode, the hosts discuss both the scientific studies and anecdotal evidence they’ve seen first hand when it comes to combining antidepressants and psilocybin. They also highlight some of the profound shifts they’ve seen in their clients as well as how microdosing can help alleviate the withdrawal symptoms associated with tapering. 


About Psychedelic Passage: Psychedelic Passage facilitates safe containers for sacred psychedelic use by creating an online ecosystem that leverages human connection to pair journeyers with a network of pre-vetted, professional guides in their local area. The company’s comprehensive vetting process ensures each hand selected facilitator serves journeyers with integrity. The goal is to inspire trust, confidence, and lasting change for each journeyer. To date, their network of guides have facilitated hundreds of safe and transformational journeys for people all across the United States. You can also learn more about the founders and hosts by viewing the bios for Nicholas Levich and Jimmy Nguyen.